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Clinical Neuroscience and Develo

Clinical Neuroscience and Development Laboratory

Research – Current Projects

Child & Adolescent ADHD
“Brain Function in ADHD and non-ADHD”
These studies look to better understand ADHD brain function by using cognitive testing and functional Magnetic Resonance Imaging (fMRI). Enrollment into these studies is currently closed. For more information, click here.

Depression & Typical Development
“Neural Architecture of Emotion Regulation, Adolescent Development and Depression”
This federally funded study uses fMRI to determine how adolescents’ brains control their emotional reactivity to better understand the multiple biological causes of depression. This study is currently enrolling right-handed teens ages 12 – 18 who are currently experiencing a depressive episode or who have experienced one in the past. It is also enrolling right-handed adolescents ages 12 – 18 who are free of any medical or psychiatric problems. For more information, click here.

“rTMS Treatment of Teens with Depression”
This study looked at the efficacy of using repetitive Transcranial Magnetic Stimulation as an alternative treatment option for teens with severe depression. Enrollment into this study is currently closed.

“Decision-Making When Working for Reward” & “Rapid Perceptual Processing of Facial Images”
These studies use fMRI and personality assessments to determine how the brain works both when people are working for rewards and viewing facial images. Enrollment into these studies is currently closed.

Hoarding Disorder
“Neural Mechanisms of CBT Response in Hoarding Disorder”
This federally-funded study is in conjunction with the Anxiety Disorders Center and seeks to better determine responses to treatment in Hoarding Disorder. This study is currently enrolling adults ages 20 - 60. For more information, click here.

Neurocognitive Development

There is a strong focus in the lab on projects that will ultimately help us better understand neural differences between younger and older groups, particularly neural development that occurs after puberty into early adult years. Numerous studies of brain structure, brain function, and cognitive test performance show developmental changes throughout this critical period of transition between childhood and adulthood. However, there is insufficient understanding of how changes in cognition and behavioral control relate to these neurobiological factors.

Multimodal Data Fusion is the process of combining data obtained from different modalities (e.g., fMRI and EEG) and integrating them in the same analytic framework. Such analyses are extremely powerful ways to maximize the usefulness of obtained datsets, as each research methodology carries its own set of strengths and limitations. By capitalizing on the qualitatively different types of information provided by each modality, it is possible to approach old questions in new ways.

 

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